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DBpedia 2015-10

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Matches in DBpedia 2015-10 for { ?s ?p "Exocytosis (/ˌɛksɵsaɪˈtoʊsɨs/) is a form of active transport in which a cell transports molecules (such as proteins) out of the cell (exo- + cytosis) by expelling them in an energy-using process. Exocytosis and its counterpart, endocytosis, are used by all cells because most chemical substances important to them are large polar molecules that cannot pass through the hydrophobic plasma or cell membrane by passive means.In exocytosis, secretory vesicles carry their contents across the cell membrane and into the extracellular space. These membrane-bound vesicles contain soluble proteins to be secreted to the extracellular environment, as well as membrane proteins and lipids that are sent to become components of the cell membrane. However, the mechanism of the secretion of intravesicular contents out of the cell is very different from the incorporation in the cell membrane of ion channels, signaling molecules, or receptors. While for membrane recycling and the incorporation in the cell membrane of ion channels, signaling molecules, or receptors complete membrane merger is required, for cell secretion there is transient vesicle fusion with the cell membrane in a process called exocytosis, dumping its contents out of the cell's environment. Examination of cells following secretion using electron microscopy demonstrate increased presence of partially empty vesicles following secretion. This suggested that during the secretory process, only a portion of the vesicular content is able to exit the cell. This could only be possible if the vesicle were to temporarily establish continuity with the cell plasma membrane, expel a portion of its contents, then detach, reseal, and withdraw into the cytosol (endocytose). In this way, the secretory vesicle could be reused for subsequent rounds of exo-endocytosis, until completely empty of its contents."@en }

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