Matches in DBpedia 2015-10 for { ?s ?p "Cerberin is a type of cardiac glycoside, a steroidal class found in the seeds of the dicotyledonous angiosperm, Cerbera odollam (also known as the suicide tree). This class includes digitalis-like agents, channel-blockers that as a group have found historic uses as cardiac treatments, but which at higher doses are extremely toxic; in the case of cerberin, consumption of the C. odollam results in poisoning with presenting nausea, vomiting, and abdominal pain, often leading to death. The natural product has been structurally characterized, its toxicity is clear—historically it has been used as an intentional human poison, and accidental poisonings with fatalities have resulted from individuals even indirectly consuming the agent—but its potentially therapeutic pharmacologic properties are very poorly described."@en }
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- Cerberin abstract "Cerberin is a type of cardiac glycoside, a steroidal class found in the seeds of the dicotyledonous angiosperm, Cerbera odollam (also known as the suicide tree). This class includes digitalis-like agents, channel-blockers that as a group have found historic uses as cardiac treatments, but which at higher doses are extremely toxic; in the case of cerberin, consumption of the C. odollam results in poisoning with presenting nausea, vomiting, and abdominal pain, often leading to death. The natural product has been structurally characterized, its toxicity is clear—historically it has been used as an intentional human poison, and accidental poisonings with fatalities have resulted from individuals even indirectly consuming the agent—but its potentially therapeutic pharmacologic properties are very poorly described.".