Matches in DBpedia 2015-10 for { ?s ?p "Canrenone (INN, USAN) (brand names Contaren, Luvion, Phanurane, Spiroletan) is a steroidal antimineralocorticoid and weak antiandrogen and progestogen related to spironolactone which is used as a diuretic in Europe.Carenone is a major active metabolite of spironolactone, canrenoic acid, and potassium canrenoate, and is believed to be partially or largely responsible for their effects.Canrenone is more potent as an antimineralocorticoid relative to spironolactone, but is considerably less potent and effective as an antiandrogen. Similarly to spironolactone, canrenone inhibits steroidogenic enzymes such as 11β-hydroxylase, cholesterol side-chain cleavage enzyme, 17α-hydroxylase, and 21-hydroxylase, but once again, is comparatively more potent in doing so.Canrenone has been found to be effective in the treatment of hirsutism in women."@en }
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- Canrenone abstract "Canrenone (INN, USAN) (brand names Contaren, Luvion, Phanurane, Spiroletan) is a steroidal antimineralocorticoid and weak antiandrogen and progestogen related to spironolactone which is used as a diuretic in Europe.Carenone is a major active metabolite of spironolactone, canrenoic acid, and potassium canrenoate, and is believed to be partially or largely responsible for their effects.Canrenone is more potent as an antimineralocorticoid relative to spironolactone, but is considerably less potent and effective as an antiandrogen. Similarly to spironolactone, canrenone inhibits steroidogenic enzymes such as 11β-hydroxylase, cholesterol side-chain cleavage enzyme, 17α-hydroxylase, and 21-hydroxylase, but once again, is comparatively more potent in doing so.Canrenone has been found to be effective in the treatment of hirsutism in women.".