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DBpedia 2015-10

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Matches in DBpedia 2015-10 for { ?s ?p "Calcium-binding proteins are proteins that participate in calcium cell signalling pathways by binding to Ca2+.Many different calcium-binding proteins exist, with different cellular and tissue distribution and involvement in specific functions.The most ubiquitous Ca2+-sensing protein, found in all eukaryotic organisms including yeasts, is calmodulin.Intracellular storage and release of Ca2+ from the sarcoplasmic reticulum is associated with the high-capacity, low-affinity calcium-binding protein calsequestrin.With their role in signal transduction, calcium-binding proteins contribute to all aspects of the cell's functioning, from homeostasis to learning and memory.For example, the neuron-specific calexcitin has been found to have an excitatory effect on neurons, and interacts with proteins that control the firing state of neurons, such as the voltage-dependent potassium channel.Compartmentalization of calcium binding proteins has been noted within cells, suggesting that these proteins perform distinct functions in localized calcium signaling. "@en }

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