Matches in DBpedia 2015-10 for { ?s ?p "A paroxysmal depolarizing shift (PDS) or depolarizing shift is a cellular manifestation of epilepsy. First, there is a Ca2+ mediated depolarization, which causes voltage gated Na+ to open, resulting in action potentials. This depolarization is followed by a period of hyper-polarization mediated by Ca2+-dependent K+ channels or GABA-activated Cl− influx.It is noteworthy that unmasking persistent sodium current in presence of Calcium channel blocker has been well established."@en }
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- Paroxysmal_depolarizing_shift comment "A paroxysmal depolarizing shift (PDS) or depolarizing shift is a cellular manifestation of epilepsy. First, there is a Ca2+ mediated depolarization, which causes voltage gated Na+ to open, resulting in action potentials. This depolarization is followed by a period of hyper-polarization mediated by Ca2+-dependent K+ channels or GABA-activated Cl− influx.It is noteworthy that unmasking persistent sodium current in presence of Calcium channel blocker has been well established.".